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Glucosamine & Chondroitin: A Proven Remedy for Joint Pain

Available as oral supplements, glucosamine and chondroitin can be effective in reducing the symptoms of arthritis. It so happens that these two naturally occurring compounds exist within human cartilage tissue. This is noteworthy because cartilage is important for enhancing mobility and comfort of movement within our bodies. It is connective tissue that “protects and cushions” the ends of bones in one’s hands, knees, spine, and almost all other joints.


Glucosamine and chondroitin can be described as highly complementary compounds; that is, they work well in tandem, which is how they are often packaged, often as “GCM.” Glucosamine is an amino sugar that plays a role in the production of certain proteins and lipids. Chondroitin is a nutrient that is common to all mammals. 

Taken as an oral supplement, glucosamine and chondroitin are touted for their combined ability to relieve osteoarthritis pain. The specific form of these two compounds commonly found in oral supplements are technically known as glucosamine sulfate and chondroitin sulfate.

The Benefits of Super Glucosamine & Chondroitin

Here is a look at how GCM can potentially treat and reduce the symptoms of osteoarthritis. Taking GCM is not meant to replace proper medical treatment where it is recommended, but in combination with it and properly supervised by a healthcare professional. If you experience osteoarthritis symptoms, talk to your doctor about GCM before trying it out for yourself. 

Glucosamine sulfate, taken orally, has been shown to provide some minor relief from arthritic knee pain, for women as well as men. 

Chondroitin sulfate has been shown to be as effective in reducing arthritic knee pain as commonly recommended NSAID medication celecoxib, according to a 2017 study. 

A 2014 review of 43 separate studies showed that GCM correlates with a 10% average lower pain score compared with a placebo. This is considered a worthy and significant difference in osteoarthritis-sourced knee pain.

Glucosamine and chondroitin are most effective when combined. Which explains why they are usually combined into a single supplement.) One of the primary ways GCM affects pain levels is by reducing inflammation in the affected joints. It is also touted to have the ability to help repair cartilage.


Among all the supplements on the market, GCM is one of those most recognized and specified supplements that could address pain from osteoarthritis. If you experience such a condition, taking a GCM supplement might be a worthwhile part of your treatment/management of your symptoms. Be sure to discuss its use with a healthcare professional before adding it to your daily regimen.


* Statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. WonderLabs always recommends reviewing any nutritional supplement changes with your primary medical provider.